Hello Friends 👋
We hope you are having a nice weekend. A new episode of journal club is ready for you! This week we review a series of interesting papers, notably the effect of azithromycin to prevent maternal and neonatal sepsis/death, screening and management of hemodynamically significant PDA from the amazing folks at the University of Iowa, and much more. We hope you enjoy this episode. Happy Sunday!
Articles discussed on this week's episode can be accessed from the links below:
Neonatal intensive care unit occupancy rate and probability of discharge of very preterm infants - Journal of Perinatology
Journal of Perinatology - Neonatal intensive care unit occupancy rate and probability of discharge of very preterm infants
Marc Beltempo
Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth - PubMed
Among women planning a vaginal delivery, a single oral dose of azithromycin resulted in a significantly lower risk of maternal sepsis or death than placebo but had little effect on newborn sepsis or death. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development…
Alan T N Tita
Impact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in “22-23” week and “24-26″ infants - PubMed
The hemodynamically significant patent ductus arteriosus (hsPDA) is a controversial topic in neonatology, particularly among neonates at the earliest gestational ages of 22<sup>+0</sup>-23<sup>+6</sup> weeks. There is little, to no data on the natural history or impact of the PDA in extremely preter…
R E GiesingerPostnatal growth restriction and neurodevelopment at 5 years of age: a European extremely preterm birth cohort study
Objective To investigate whether extrauterine growth restriction (EUGR) during the neonatal hospitalisation by sex among extremely preterm (EPT) infants is associated with cerebral palsy (CP) and cognitive and motor abilities at 5 years of age. Study design Population-based cohort of births <28 wee…
Platelet Transfusions in a Multi-Neonatal Intensive Care Unit Health Care Organization Before and After Publication of the PlaNeT-2 Clinical Trial - PubMed
Changing platelet transfusion guidelines in a multi-NICU network to a more restrictive practice was not associated with a significant reduction in number of neonates receiving a platelet transfusion. The guideline implementation was associated with a reduction in the mean platelet count triggering a…
Timothy M BahrBen's notes can be downloaded here 👇: