Hello Friends 👋
We hope you enjoy this week's Journal Club. Unintentionally, this week's episode has a strong infectious disease feel to it. We talk about using oral antibiotics in neonates with suspected infections, bacterial colonization of OG vs NG, the implications of drawing blood cultures from both central cathethers and peripheral site, and epidemiology of neonatal COVID in the US. We also reviewed other very intersting articles. Please make sure to collect your CME credit for this week and we hope to see you Monday for another week of neonatology review podcasts
Have a good sunday !
Claim your CME credit here:
Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial
An early intravenous-to-oral antibiotic switch with amoxicillin–clavulanic acid isnon-inferior to a full course of intravenous antibiotics in neonates with probablebacterial infection and is not associated with an increased incidence of adverse events.
A comparison of bacterial colonization between nasogastric and orogastric enteral feeding tubes in infants in the neonatal intensive care unit - Journal of Perinatology
Journal of Perinatology - A comparison of bacterial colonization between nasogastric and orogastric enteral feeding tubes in infants in the neonatal intensive care unit
Kannikar Vongbhavit
Dual-site blood culture yield and time to positivity in neonatal late-onset sepsis
Objective To determine whether culture yield and time to positivity (TTP) differ between peripheral and central vascular catheter-derived blood cultures (BCx) in neonatal intensive care unit (NICU) patients evaluated for late-onset sepsis. Design Single-centre, retrospective, observational study.…
Epidemiology of Neonatal COVID-19 in the United States
OBJECTIVES:. Data on coronavirus disease 2019 (COVID-19) infections in neonates are limited. We aimed to identify and describe the incidence, presentation, and clinical outcomes of neonatal COVID-19.METHODS:. Over 1 million neonatal encounters at 109 United States health systems, from March 2020 to…
Joan Devin, BSc
Age at First Extubation Attempt and Death or Respiratory Morbidities in Extremely Preterm Infants
To describe the timing of first extubation in extremely preterm infants and explorethe relationship between age at first extubation, extubation outcome, and death/respiratorymorbidities.
Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders
This population-based cohort study examines whether antenatal maternal corticosteroid treatment is associated with psychological developmental and neurosensory disorders among children born term and preterm and whether the associations persist in a sibling-comparison design.
For Authors
Blood pressure values and hypotension management in extremely preterm infants: a multi-center study - Journal of Perinatology
Journal of Perinatology - Blood pressure values and hypotension management in extremely preterm infants: a multi-center study
Eric S. Peeples