Hello Friends đź‘‹
I wanted to start off by thanking all of you for supporting the incubator and specifically, our most recent initiative to help Ukrainian NICUs affected by the war.
This week, we have several impactful papers. We review the use of a novel rsv prophylaxis agent in both preterm and term infants. We review the possible benefits of enteral insulin supplementation to attainment of full enteral feeds. We review also a fascinating paper looking at the impact of genetic testing on our decision making in the ICU. And is it really okay to use cotton balls to collect urine samples in nicu babies?
Enjoy ! 🤓
Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants | NEJM
Original Article from The New England Journal of Medicine — Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants

Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants | NEJM
Original Article from The New England Journal of Medicine — Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants

Safety of Nirsevimab for RSV in Infants with Heart or Lung Disease or Prematurity | NEJM
Correspondence from The New England Journal of Medicine — Safety of Nirsevimab for RSV in Infants with Heart or Lung Disease or Prematurity

Influence of Genetic Information on Neonatologists’ Decisions: A Psychological Experiment
10.1542/6282514622001Video AbstractPEDS-VA_2021-0521306282514622001BACKGROUND AND OBJECTIVES. Genetic testing is expanding among ill neonates, yet the influence of genetic results on medical decision-making is not clear. With this study, we sought to determine how different types of genetic informat…
Efficacy and Safety of Enteral Recombinant Human Insulin in Preterm Infants
This randomized clinical trial investigates whether feeding intolerance in preterm infants can be reduced with the addition of recombinant human insulin to human milk and preterm formula.

Use of cotton balls in diapers for collection of urine samples impacts the analysis of routine chemistry tests: an evaluation of cotton balls, diapers, and chemistry analyzers
To evaluate the suitability of urine samples collected with cotton balls placed intodiapers for routine laboratory chemistry analyses.

Sixth-Hour Trancutaneous Bilirubin and Need for Phototherapy in DAT Positive Newborns
OBJECTIVES. To characterize the outcomes of ABO incompatible direct antiglobulin test (DAT) positive newborns and determine the predictive ability of a sixth-hour transcutaneous bilirubin (TcB for needing phototherapy ≤24 hours of age.METHODS. Retrospective, cross-sectional study from May 2013 to Ma…
Discharge planning of the preterm infant | Canadian Paediatric Society
“When will my baby come home?” is one of the most common questions asked by parents of preterm infants admitted to the neonatal intensive care unit (NICU). While the hospital course varies based on the gestational age at birth and the attainment of “physiological maturity”, the aim of this statement…

Improving Time to Independent Oral Feeding to Expedite Hospital Discharge in Preterm Infants
BACKGROUND AND OBJECTIVES. Achievement of independent oral feedings remains the most common barrier to discharge in preterm infants. Early oral feeding initiation may be associated with a lower postmenstrual age (PMA) at independent oral feeding and discharge. In preterm infants born between 25 and…