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#106-110 - BPD Definitions

Hello Friends 👋

This week on the Incubator and Neonatology Review podcast we discuss the evolution of BPD definitions throughout the years. Daphna and I realize that it can get quite confusing to sort out which definition is which and why there is even a need to have so many ways to define one disease. This week we have the pleasure of having Dr. Kent Willis as our expert and he talked to us about gut-lung axis and how this influencing our understanding of BPD. If BPD is a topic you particularly enjoy, we highly recommend you check out the interview we released last year with Dr. Erik Jensen and that is available here: 

Thank you all for your support.

Make sure to grab this week's PowerPoint presentation.


Link to download the PowerPoint and notes from these episodes 👇

The articles covered on this series of episodes can be found here 👇

Safety, reliability, and validity of a physiologic definition of bronchopulmonary dysplasia.

Walsh MC, Wilson-Costello D, Zadell A, Newman N, Fanaroff A.J Perinatol. 2003 Sep;23(6):451-6. doi: 10.1038/ 13679930

A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children's Hospitals Neonatal Consortium Severe BPD Group.

Vyas-Read S, Logan JW, Cuna AC, Machry J, Leeman KT, Rose RS, Mikhael M, Wymore E, Ibrahim JW, DiGeronimo RJ, Yallapragada S, Haberman BE, Padula MA, Porta NF, Murthy K, Nelin LD, Coghill CH, Zaniletti I, Savani RC, Truog W, Engle WA, Lagatta JM.J Perinatol. 2022 Jan;42(1):58-64. doi: 10.1038/s41372-021-01178-4. Epub 2021 Aug 5.PMID: 34354227 Free PMC article.

Abnormal pulmonary outcomes in premature infants: prediction from oxygen requirement in the neonatal period.

Shennan AT, Dunn MS, Ohlsson A, Lennox K, Hoskins EM.Pediatrics. 1988 Oct;82(4):527-32.PMID: 3174313

Bronchopulmonary Dysplasia: Executive Summary of a Workshop.

Higgins RD, Jobe AH, Koso-Thomas M, Bancalari E, Viscardi RM, Hartert TV, Ryan RM, Kallapur SG, Steinhorn RH, Konduri GG, Davis SD, Thebaud B, Clyman RI, Collaco JM, Martin CR, Woods JC, Finer NN, Raju TNK.J Pediatr. 2018 Jun;197:300-308. doi: 10.1016/j.jpeds.2018.01.043. Epub 2018 Mar 16.PMID: 29551318 Free PMC article. No abstract available.

Pathology of arrested acinar development in postsurfactant bronchopulmonary dysplasia.

Husain AN, Siddiqui NH, Stocker JT.Hum Pathol. 1998 Jul;29(7):710-7. doi: 10.1016/s0046-8177(98)90280-5.PMID: 9670828

The definition of bronchopulmonary dysplasia: an evolving dilemma.

Ibrahim J, Bhandari V.Pediatr Res. 2018 Nov;84(5):586-588. doi: 10.1038/s41390-018-0167-9. Epub 2018 Sep 4.PMID: 30188504

Revisiting the Definition of Bronchopulmonary Dysplasia: Effect of Changing Panoply of Respiratory Support for Preterm Neonates.

Isayama T, Lee SK, Yang J, Lee D, Daspal S, Dunn M, Shah PS; Canadian Neonatal Network and Canadian Neonatal Follow-Up Network Investigators.JAMA Pediatr. 2017 Mar 1;171(3):271-279. doi: 10.1001/jamapediatrics.2016.4141.PMID: 28114678

The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach.

Jensen EA, Dysart K, Gantz MG, McDonald S, Bamat NA, Keszler M, Kirpalani H, Laughon MM, Poindexter BB, Duncan AF, Yoder BA, Eichenwald EC, DeMauro SB.Am J Respir Crit Care Med. 2019 Sep 15;200(6):751-759. doi: 10.1164/rccm.201812-2348OC.PMID: 30995069 Free PMC article.

Bronchopulmonary dysplasia.

Jobe AH, Bancalari E.Am J Respir Crit Care Med. 2001 Jun;163(7):1723-9. doi: 10.1164/ajrccm.163.7.2011060.PMID: 11401896 No abstract available.

Pulmonary disease following respirator therapy of hyaline-membrane disease. Bronchopulmonary dysplasia.

Northway WH Jr, Rosan RC, Porter DY.N Engl J Med. 1967 Feb 16;276(7):357-68. doi: 10.1056/NEJM196702162760701.PMID: 5334613 No abstract available.

Alan H. Jobe; The New BPD. Neoreviews October 2006; 7 (10): e531–e545.

Learn more about the Willis Lab

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