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#125-129 - Intraventricular Hemorrhage

Hello Friends,

This week we have a great series of episodes covering the topic of intraventricular hemorrhage in preterm infants. We covered a broad topic and thank Dr. Weiss from the University of Florida for making himself available to our show and answering questions on Thursday. Please make sure to grab this week's PowerPoint presentation for this week's series of episodes. Enjoy!

Find out more about our guest this week, Dr. Michael Weiss from the division of neonatology at the University of Florida:

Link to download the PowerPoint and notes from these episodes 👇

The articles covered on this series of episodes can be found here 👇

Randomized trial of drainage, irrigation and fibrinolytic therapy for premature infants with posthemorrhagic ventricular dilatation: developmental outcome at 2 years.

Whitelaw A, Jary S, Kmita G, Wroblewska J, Musialik-Swietlinska E, Mandera M, Hunt L, Carter M, Pople I.Pediatrics. 2010 Apr;125(4):e852-8. doi: 10.1542/peds.2009-1960. Epub 2010 Mar 8.PMID: 20211949 Clinical Trial.

Phase 1 trial of prevention of hydrocephalus after intraventricular hemorrhage in newborn infants by drainage, irrigation, and fibrinolytic therapy.

Whitelaw A, Pople I, Cherian S, Evans D, Thoresen M.Pediatrics. 2003 Apr;111(4 Pt 1):759-65. doi: 10.1542/peds.111.4.759.PMID: 12671109 Clinical Trial.

Intraventricular Hemorrhage and White Matter Injury in Preclinical and Clinical Studies.

Romantsik O, Bruschettini M, Ley D.Neoreviews. 2019 Nov;20(11):e636-e652. doi: 10.1542/neo.20-11-e636.PMID: 31676738 Review.

Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm.

Papile LA, Burstein J, Burstein R, Koffler H.J Pediatr. 1978 Apr;92(4):529-34. doi: 10.1016/s0022-3476(78)80282-0.PMID: 305471

Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.

McGoldrick E, Stewart F, Parker R, Dalziel SR.Cochrane Database Syst Rev. 2020 Dec 25;12(12):CD004454. doi: 10.1002/14651858.CD004454.pub4.PMID: 33368142 Free PMC article.

Drainage, irrigation and fibrinolytic therapy (DRIFT) for posthaemorrhagic ventricular dilatation: 10-year follow-up of a randomised controlled trial.

Luyt K, Jary SL, Lea CL, Young GJ, Odd DE, Miller HE, Kmita G, Williams C, Blair PS, Hollingworth W, Morgan M, Smith-Collins AP, Walker-Cox S, Aquilina K, Pople I, Whitelaw AG.Arch Dis Child Fetal Neonatal Ed. 2020 Sep;105(5):466-473. doi: 10.1136/archdischild-2019-318231. Epub 2020 Jul 4.PMID: 32623370 Free PMC article. Clinical Trial.

Reducing Germinal Matrix-Intraventricular Hemorrhage: Perinatal and Delivery Room Factors.

Lim J, Hagen E.Neoreviews. 2019 Aug;20(8):e452-e463. doi: 10.1542/neo.20-8-e452.PMID: 31371554

Association of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping With Death or Severe Intraventricular Hemorrhage Among Preterm Infants.

Katheria A, Reister F, Essers J, Mendler M, Hummler H, Subramaniam A, Carlo W, Tita A, Truong G, Davis-Nelson S, Schmölzer G, Chari R, Kaempf J, Tomlinson M, Yanowitz T, Beck S, Simhan H, Dempsey E, O'Donoghue K, Bhat S, Hoffman M, Faksh A, Arnell K, Rich W, Finer N, Vaucher Y, Khanna P, Meyers M, Varner M, Allman P, Szychowski J, Cutter G.JAMA. 2019 Nov 19;322(19):1877-1886. doi: 10.1001/jama.2019.16004.PMID: 31742630 Free PMC article. Clinical Trial.

Neurologic signs in neonatal intraventricular hemorrhage: a correlation with real-time ultrasound.

Dubowitz LM, Levene MI, Morante A, Palmer P, Dubowitz V.J Pediatr. 1981 Jul;99(1):127-33. doi: 10.1016/s0022-3476(81)80977-8.PMID: 7252649

Indomethacin Prophylaxis in Preterm Infants: Changes over Time.

Curtis SF, Cotten CM, Laughon M, Younge N, Peterson J, Clark RH, Greenberg RG.Am J Perinatol. 2022 Oct 19. doi: 10.1055/a-1925-5173. Online ahead of print.PMID: 35973793

Intraventricular hemorrhage in premature infants: mechanism of disease.

Ballabh P.Pediatr Res. 2010 Jan;67(1):1-8. doi: 10.1203/PDR.0b013e3181c1b176.PMID: 19816235 Free PMC article. Review.

Andrew Whitelaw; Core Concepts: Intraventricular Hemorrhage. Neoreviews February 2011; 12 (2): e94–e101.

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